Voice Analysis: Schizophrenia

  • Parola, Simonsen, Bliksted, & Fusaroli (2020)
  • Voice patterns in schizophrenia: A systematic review and Bayesian meta-analysis
  • N papers = 27, N effect sizes = 81, N participants = 1714
  • Last updated: 2020-12-19
  • Curator(s): LNJ, ND
  • Search Strategy: "We adopted the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Guidelines (PRISMA, Stewart et al., 2015) for trans- parent reporting of a systematic review. We pre-registered our protocol by specifying a priori the study rationale, eligibility criteria, search strat- egy, moderator variables, and statistical analyses (see https://bit.ly/ 2EEFeQZ). The literature search was conducted on Pubmed and Google Scholar, the latter including dissertations and unpublished manuscripts. The search terms used were (prosody OR inflection OR intensity OR pitch OR fundamental frequency OR speech rate OR voice quality OR acoustic OR intonation OR vocal) AND (schizo*). The search was con- ducted on August 21 2017, and updated on April 12 2018. We complemented the list by performing a backward and forward literature search: we screened the bibliography of the papers found, and the papers citing them as identified by Google Scholar. Articles were screened for eligibility by two authors (AP and AS).Study selection was conducted according to the following inclusioncriteria: (a) empirical study, (b) quantification of acoustic features inthe vocal production of participants with schizophrenia orschizoaffective disorder1(c) sample including at least two individualswith schizophrenia or schizoaffective disorder, (d) inclusion of a non-clinical comparison group, or an assessment of variation in acoustic fea-tures in relation to severity of clinical features. Clinical comparisongroups (e.g. with depression) were excluded because the limited num-ber of studies did not permit meta-analytic estimations" (Parola et al., 2020)
  • Systematic: yes
  • Voice features: speech_duration, speech_rate, speech_percentage, pause_duration, pause_number, pause_total_length, response_latency, pause_variability, pitch, pitch_variability, pitch_range, f1, f2, f3, f4, f5, f6, formant_bandwidth, formant_amplitude, intensity, intensity_variability

Pinheiro, A.P., Rezaii, N., Rauber, A., Niznikiewicz, M., 2016. Is this my voice or yours? The role of emotion and acoustic quality in self-other voice discrimination in schizophrenia. Cogn. Neuropsychiatry 21, 335–353.

Rapcan, V., D’Arcy, S., Yeap, S., Afzal, N., Thakore, J., & Reilly, R. B. (2010). Acoustic and temporal analysis of speech: A potential biomarker for schizophrenia. Medical engineering & physics, 32(9), 1074-1079.

Cohen, A. S., Mitchell, K. R., Strauss, G. P., Blanchard, J. J., Buchanan, R. W., Kelly, D. L., ... & Carpenter, W. T. (2017). The effects of oxytocin and galantamine on objectively-defined vocal and facial expression: Data from the CIDAR study. Schizophrenia research, 188, 141.

Pinheiro, A. P., Rezaii, N., Rauber, A., Nestor, P. G., Spencer, K. M., & Niznikiewicz, M. (2017). Emotional self–other voice processing in schizophrenia and its relationship with hallucinations: ERP evidence. Psychophysiology, 54(9), 1252-1265.

Kliper, R., Portuguese, S., & Weinshall, D. (2015, September). Prosodic analysis of speech and the underlying mental state. In International Symposium on Pervasive Computing Paradigms for Mental Health (pp. 52-62). Springer, Cham.

Cohen, A. S., Alpert, M., Nienow, T. M., Dinzeo, T. J., & Docherty, N. M. (2008). Computerized measurement of negative symptoms in schizophrenia. Journal of psychiatric research, 42(10), 827-836.

Alpert, M., Rosenberg, S. D., Pouget, E. R., & Shaw, R. J. (2000). Prosody and lexical accuracy in flat affect schizophrenia. Psychiatry research, 97(2-3), 107-118.

Alpert, M., Clark, A., & Pouget, E. R. (1994). The syntactic role of pauses in the speech of schizophrenic patients with alogia. Journal of Abnormal Psychology, 103(4), 750.

Mandal, M. K., Srivastava, P., & Singh, S. K. (1990). Paralinguistic characteristics of speech in schizophrenics and depressives. Journal of psychiatric research, 24(2), 191-196.

Tavano, A., Sponda, S., Fabbro, F., Perlini, C., Rambaldelli, G., Ferro, A., ... & Brambilla, P. (2008). Specific linguistic and pragmatic deficits in Italian patients with schizophrenia. Schizophrenia Research, 102(1-3), 53-62.

Perlini, C., Marini, A., Garzitto, M., Isola, M., Cerruti, S., Marinelli, V., ... & Bellani, M. (2012). Linguistic production and syntactic comprehension in schizophrenia and bipolar disorder. Acta Psychiatrica Scandinavica, 126(5), 363-376.

Rutter, D. R. (1977). Speech patterning in recently admitted and chronic long‐stay schizophrenic patients. British Journal of Social and Clinical Psychology, 16(1), 47-55.

St-Hilaire, A., Cohen, A. S., & Docherty, N. M. (2008). Emotion word use in the conversational speech of schizophrenia patients. Cognitive neuropsychiatry, 13(4), 343-356.

Docherty, N. M. (2012). Missing referents, psychotic symptoms, and discriminating the internal from the externalized. Journal of abnormal psychology, 121(2), 416.

Wan, M. W., Penketh, V., Salmon, M. P., & Abel, K. M. (2008). Content and style of speech from mothers with schizophrenia towards their infants. Psychiatry Research, 159(1-2), 109-114.

Rochester, S. R., Thurston, S., & Rupp, J. (1977). Hesitations as clues to failures in coherence: A study of the thought-disordered speaker. Sentence Production: Developments in theory and research.

Salomé, F., Boyer, P., & Fayol, M. (2002). Written but not oral verbal production is preserved in young schizophrenic patients. Psychiatry research, 111(2-3), 137-145.

Bernardini, F., Lunden, A., Covington, M., Broussard, B., Halpern, B., Alolayan, Y., ... & Attademo, L. (2016). Associations of acoustically measured tongue/jaw movements and portion of time speaking with negative symptom severity in patients with schizophrenia in Italy and the United States. Psychiatry Research, 239, 253-258.

Martínez-Sánchez, F., Muela-Martínez, J. A., Cortés-Soto, P., Meilán, J. J. G., Ferrándiz, J. A. V., Caparrós, A. E., & Valverde, I. M. P. (2015). Can the acoustic analysis of expressive prosody discriminate schizophrenia?. The Spanish journal of psychology, 18.

Alpert, M., Shaw, R. J., Pouget, E. R., & Lim, K. O. (2002). A comparison of clinical ratings with vocal acoustic measures of flat affect and alogia. Journal of Psychiatric Research, 36(5), 347-353.

Cannizzaro, M. S., Cohen, H., Rappard, F., & Snyder, P. J. (2005). Bradyphrenia and bradykinesia both contribute to altered speech in schizophrenia: a quantitative acoustic study. Cognitive and behavioral neurology, 18(4), 206-210.

Resnick, H. S., & Oltmanns, T. F. (1984). Hesitation patterns in the speech of thought-disordered schizophrenic and manic patients. Journal of Abnormal Psychology, 93(1), 80.

McGilloway, S., Cooper, S. J., & Douglas-Cowie, E. (2003). Can patients with chronic schizophrenia express emotion? A speech analysis. Schizophrenia research, 64(2-3), 189.

Cohen, A. S., Kim, Y., & Najolia, G. M. (2013). Psychiatric symptom versus neurocognitive correlates of diminished expressivity in schizophrenia and mood disorders. Schizophrenia research, 146(1-3), 249-253.

Cohen, A. S., Najolia, G. M., Kim, Y., & Dinzeo, T. J. (2012). On the boundaries of blunt affect/alogia across severe mental illness: implications for Research Domain Criteria. Schizophrenia research, 140(1-3), 41-45.

Alpert, M., Kotsaftis, A., & Pouget, E. R. (1997). Speech fluency and schizophrenic negative signs. Schizophrenia Bulletin, 23(2), 171-177.

Matsumoto, K., Kircher, T., Stokes, P., Brammer, M. J., LIddle, P., & McGuire, P. K. (2013). Frequency and neural correlates of pauses in patients with formal thought disorder. Frontiers in psychiatry, 4, 127.

Alpert, M., Pouget, E. R., & Silva, R. (1995). Cues to the assessment of affects and moods: Speech fluency and pausing. Psychopharmacology bulletin.

Çokal, D., Zimmerer, V., Turkington, D., Ferrier, N., Varley, R., Watson, S., & Hinzen, W. (2019). Disturbing the rhythm of thought: Speech pausing patterns in schizophrenia, with and without formal thought disorder. PloS one, 14(5), e0217404.

Graux, J., Courtine, J. B., Bruneau, N., Camus, V., & El-Hage, W. (2015). Higher fundamental voice frequency is related to extrapyramidal symptoms in schizophrenia. Schizophrenia research, 2(161), 517-518.

Tolkmitt, F., Helfrich, H., Standke, R., & Scherer, K. R. (1982). Vocal indicators of psychiatric treatment effects in depressives and schizophrenics. Journal of communication disorders, 15(3), 209-222.

Martínez, A., Felizzola Donado, C. A., & Matallana Eslava, D. L. (2015). Spontaneous speech prosody and discourse analysis in schizophrenia and Fronto Temporal Dementia (FTD) patients. Revista colombiana de psiquiatria, 44(1), 13-19.

Le, T. P. (2018). Vocal Expression In Schizophrenia: Examining The Role Of Vocal Accommodation In Clinical Ratings Of Speech.

Zhang, J., Zhongde, P. A. N., Chao, G. U. I., Jie, Z. H. U., & Donghong, C. U. I. (2016). Clinical investigation of speech signal features among patients with schizophrenia. Shanghai archives of psychiatry, 28(2), 95.

Compton, M. T., Lunden, A., Cleary, S. D., Pauselli, L., Alolayan, Y., Halpern, B., ... & Bernardini, F. (2018). The aprosody of schizophrenia: Computationally derived acoustic phonetic underpinnings of monotone speech. Schizophrenia research, 197, 392-399.

Ross, E. D., Orbelo, D. M., Cartwright, J., Hansel, S., Burgard, M., Testa, J. A., & Buck, R. (2001). Affective-prosodic deficits in schizophrenia: profiles of patients with brain damage and comparison with relation to schizophrenic symptoms. Journal of Neurology, Neurosurgery & Psychiatry, 70(5), 597-604.

Meaux, L. T., Mitchell, K. R., & Cohen, A. S. (2018). Blunted vocal affect and expression is not associated with schizophrenia: A computerized acoustic analysis of speech under ambiguous conditions. Comprehensive Psychiatry, 83, 84-88.

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